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ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will boost the stage or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterised by vasospasm and tissue ischemia has long been linked to coadministration of ritonavirPublic overall health risks related to the 5 substan

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